1Cohen B, Barkan D, Levy Y, et al. Leptin induces angiopoietin-2 expression in adipose tissues. J Biol Chem,2001,276:7697~7700.
2Maisonpierne PC, Suri C, Jones PF, et al. Angiopoietin-2 a natural antagonist for Tie-2 that disrupts in vivo angiogenesis.Science, 1997, 177: 55260.
3Valenzuela DM , Griffiths JA , Rojas J , et al . Angiopoietin - 3 and 4: diverging gene counterparts in mice and humans. Proc Natl Acad Sci USA, 1999, 96 (5): 1904~1909.
4Fadel BM, Boute SC, Quertermous T. Functional analysisi of the endothelial cell-specific Tie2/Tek promoter identifies unique protein-binding elements. Biochem J, 1998, 330: 335~343.
5Siobhan Loughna, Thomas N. Sato Angiopoietin and Tie signaling pathways in vascular Development. Matrix Biology, 2001,319~325.
6Jones N, Master Z, Jones J,et al. Identification of Tek-Tie2 binding partners binding to a multifunctional dockingsite mediates cell survival and migration. J Biol Chem, 1999,274: 30896~30905.
7Papapetropoulos A, Fulton D, Mahboubi K, et al. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt-survivin pathway. J Biol Chem, 2000, 275: 9102~9105.
8Jones N, Dumont D J. The Tek-Tie2 receptor signals through a novel Dok-related docking protein. Dok-R Oncogene, 1998,17: 1097~1108.
9HuangL, TurckCW, RaoP, etal. GRB2andSH-PTP2: potentially important endothelial signaling molecules downstream of the TEK-TIE2 receptor tyrosine kinase. Oncogene, 1995, 11:2097~2103.
10Lindahl P, Johansson BR, Leveen P, et al. Pericyteloss and microaneurysm formation in PDGF-B-deficientmice. Science,1997, 277: 242~245.