期刊文献+

蛋白质、多肽类药物控制释放体系的研究 被引量:7

Studies on Controlled Drug Release of Protein and Peptides
下载PDF
导出
摘要 近年来 ,蛋白质、多肽类药物广泛应用于各类疾病的治疗。本文对聚乙二醇修饰的蛋白质及蛋白质类药物控制释放这两大体系的研究进展做了较系统的总结和评述 ,并就更高级的靶向、易吸收的蛋白质药物体系的发展进行了展望。 In recent years, protein and peptides have been ex tensive applied in various treatment of disease. This paper reviewed the prote in and peptides PEGlations and the controlled release system. Furthermore, prosp ected the advanced targeted and more absorbable protein and peptides system.
出处 《高分子通报》 CAS CSCD 2005年第1期14-19,共6页 Polymer Bulletin
  • 相关文献

参考文献2

二级参考文献13

  • 1王浩,侯惠民.多肽与蛋白质类药物给药系统的研究现状[J].中国医药工业杂志,1994,25(9):421-425. 被引量:13
  • 2Kim SW,Bae YH,Okano T.Hydrogels:Swelling,drug loading,and release [J]. Pharm Res,1992,9(3):283-290.
  • 3Seppas NA, Bures P, Leobandung W, et al.Hydrogels in pharmaceutical formulation [J].Eur J Pharm Biopharm,2000,50:27-46.
  • 4Lowman AM,Morishita M,Kajita M,et al.Oral delivery of insulin using pH-responsive complexation gels [J].J Pharm Sci,1999,88(9):933-937.
  • 5Xu H, Ding PT,Wei G, et al. Preparation and some physiochemical properties of cross-linked poloxamer hydrogel spheres [J].Drug Dev Ind Pharm,2001,27(2):171-174.
  • 6Bell CL,Peppas NA.Modulation of drug permeation through interpolymer complexed hydrogels for drug delivery application [J]. J Control Release,1996,39:201-207.
  • 7Govender T, Ehtezazi T, Stolnik S, et al. Complex formation between the anionic polymer (PAA) and a cationic drug (procaine HCl): Characterization by microcalorimetric studies [J].Pharm Res,1999,16(7):1125-1131.
  • 8Bromberg L. Crosslinked poly(ethylene glycol) networks as reservoirs for protein delivery [J]. J Appl Polym Sci,1996,59(3):459-466.
  • 9Bai JPF, Chang LL, Guo JH. Effects of polyacrylic polymers on the lumenal proteolysis of peptide drugs in the colon [J]. J Pharm Sci, 1995,84(11):1291-1294.
  • 10Park K. Controlled drug delivery [M]. Washington DC: ACS,1997. 252.

共引文献48

同被引文献120

引证文献7

二级引证文献50

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部