儿童幽门螺杆菌感染的相关因素研究

A Study on Factors of Helicobacter Pylori Infection Among Children

目的 了解儿童幽门螺杆菌 (H .pylori)感染的影响因素 ,为其防治工作提供理论依据。方法 对不同民族儿童 2 78例采用ELISA法及免疫印迹法联合检测血清抗体以了解H .pylori感染状态 ,并采用问卷的方法对儿童的父母进行调查 ,了解影响儿童H .pylori感染可能的相关因素。结果 少数民族儿童 2 78名H .pylori感染的总阳性率为 64.4%(1 79/ 2 78)。经单因素分析后发现 ,年龄增长、父亲受教育年限低、多人口数家庭、居住地无公厕设施、养狗者等的H .pylori阳性率较高。多因素的Logistic回归分析显示年龄、养狗是H .pylori感染的相关因素。结论 年龄、父亲受教育年限、家庭人口数、居住地公厕设施、养狗等可能是儿童H .pylori感染的相关因素。

Objective To investigate the factors of Helicobacter pylori (H. pylori) infection, and to provide theoretical basis for its prevention and control. Methods ELISA and Western immunoblot assay were adopted to examine 278 children of different nationalities. Their parents were interviewed about relevant factors for infection by using an administered questionnaire. Results The prevalence of H. pylori was 64.4%(179/278). Univariate analysis showed high prevalence of H. pylori correlated with the factors of increased age, poor education background of fathers,big family, absence of public lavatory service and dog keeping. Multiple logistic regression analysis indicated that age and dog keeping were the relevant factors for H. pylori infection. Conclusion H. pylori infection for children is correlate with age, fathers' education background, number of members of family, public lavatory service and dog keeping.