摘要
生物制造工程是以制造复杂组织和器官为目标的交叉学科研究领域。它运用现代制造科学与生命科学的原理与方法,通过细胞的受控三维组装制造活的组织和器官,修复或替代人体的病损组织和器官。细胞组装技术是生物制造工程的关键技术,它包括两类技术路线:细胞直接组装和细胞间接组装。该文阐述了生物制造工程的原理和方法,分析了国内外研究进展,并介绍了清华大学生物制造工程研究所的研究工作。
Organism manufacturing engineering is an interdisciplinary research area which aims to manufacture complicated tissues and organs. This technology constructs living tissues and organs through controlled assembly of 3D cell structures with the principles and methods of modern manufacturing science and life sciences. To replace or repair tissues and organs, cell assembly technology is the pivotal technology in organism manufacturing engineering. This paper describes the principles used in organism manufacturing and analyzes the research trends. The research in the center of organism manufacturing engineering in Tsinghua university is also introduced.
出处
《清华大学学报（自然科学版）》
EI
CAS
CSCD
北大核心
2005年第2期145-150,共6页
Journal of Tsinghua University(Science and Technology)
基金
国家自然科学基金资助项目(30400099)
国家教育振兴计划资助项目(JC2003015)
关键词
机械制造工艺
生物制造工程
细胞直接组装
细胞间接组装
组织
器官
mechanical manufacturing technology
organism manufacturing
direct cell assembly
indirect cell assembly
tissue
organ
