摘要
以胆甾醇为原料,经硝化、还原、消除等反应以及用I_2-AgOAc-H_2O氧化引进2β,3β-二羟基的方法,立体选择性地合成了具有栗甾酮A/B环结构单元的类似物2β,3β-二羟基-6-胆甾酮。
2β, 3β-Dihydroxy-6-cholesterone, a structural analogue in A/B rings of castasterone was stereoselectively synthesized from cholesterol via nitration, reduction; elimination and oxidation reactions. The key step in the synthesis is the introduction of 2β, 3β-dihydroxy groups by oxidation with I_2-AgOAe-H_2O.
出处
《应用化学》
CAS
CSCD
北大核心
1993年第1期12-15,共4页
Chinese Journal of Applied Chemistry
关键词
二羟基胆甾酮
栗甾酮
生长促进剂
2β, 3β-dihydroxycholesterone, castasterone, A/B ring analogue, I_2-AgOAc oxidation,synthesis