实验性肠炎沙门氏菌病鸭口服中草药制剂后体内抗氧化酶活性和脂质过氧化物的变化

Changes of the activity of SOD and the content of MDA in the ducks infected with Salmonlla enteritidis

7日龄仙湖 3号雏鸭人工感染肠炎沙门氏菌 ,发病后于饮水中加入中草药煎液。分别于攻毒后15、39、6 3、87h颈静脉采血 ,取血清 ,后捕杀 ,取肺脏制成肺组织匀浆液 ,测定血清和肺组织中超氧化物歧化酶(SOD)和丙二醛 (MDA)的含量。结果攻毒后未进行治疗组鸭体内的SOD活性明显降低 ,MDA含量明显升高 ,抗生素治疗组鸭只体内的SOD活性比中草药治疗组显著降低 ,说明药物在治疗感染的同时也影响了机体内自由基的活动 ,而中草药在调节机体内环境平衡方面具有一定的优势 。

Seven-day-old duck were infected with Salmonlla Enteritidis. The disease occurred 6 hours late, The way was used to study the sensitivity of Salmonlla enteritidis to traditional Chinese herbal medicine and antibiotic and therapeutic effect of artificial infected duck by sifting drug and initial exploring drug action mechanism by determinating activity of SOD and the content of MDA in lung tissue and serum of sick duck.