儿童风湿病患者肺炎支原体感染的研究

Study on the infection of mycoplasmae pneumonia in the children with rheumatic diseases

目的探讨肺炎支原体感染与风湿病发病之间的相关性。方法收集 31例儿童风湿病患儿及 30例正常对照组 ,应用酶联免疫吸附技术 (ELISA)检测血清肺炎支原体 (MP)IgM、IgA抗体。结果风湿病患儿组MP IgM阳性 16例 (5 1.6 % ) ,MP IgA阳性10例 (36 .2 6 % ) ,正常对照组MP IgM、IgA阳性各 2例 (6 .6 7% )。风湿病患儿组肺炎支原体感染明显高于正常对照组 (P <0 .0 1和P <0 .0 5 )。结论肺炎支原体是小儿风湿病患儿感染的常见病原体 ,可能参与其发病机制。

Objective To explore the relationship between the Mycoplasmae Pneumonia(MP) infection and rheumatic diseases. Methods Specific MP-IgM, MP-IgA antibody of 31 cases with rheumatic diseases and 30 controls were assayed with ELISA. Results 16 cases (51.6%)were MP-IgM positive;10 cases(36.26%) were MP-IgA positive in rheumatic diseases group. 2 cases (6.67%) were MP-IgM or MP-IgA positive in controls.The morbidity of MP infection in rheumatic group was higher than that of controls. Conclusion The resullts indicate that MP may be the common pathogen in the children with rheumatic diseases and contribute to its the pathogenic machanism.