摘要
目的 :调查 2 0 0 3年 5月 2 3日～ 6月 15日在四川省德阳市发生的 81例毒蘑菇中毒事件并进行标本鉴定和毒素分析 ;方法 :现场采集标本进行形态学鉴定 ,利用高效液相色谱技术对蘑菇子实体、病人血液、病人透析液进行鹅膏肽类毒素检测 ;结果 :调查表明导致中毒的是鹅膏属中的异味鹅膏 (AmanitakotohiraensisNagasawa&Mitani) ,异味鹅膏子实体含有鹅膏肽类毒素的两种主要致死毒素 ,即α -鹅膏毒肽 (a -amanitin) ,β -鹅膏毒肽 (β -amanitin) ,其含量分别为196 4 2、 6 2 76 μg/g干重子实体 ,被检的 3个病人中有 1个病人的血液检测出含有 β -鹅膏毒肽 ,被检病人的透析液中未检测到毒素 ;结论 :异味鹅膏为有毒蘑菇 ,采食时要注意区分 ,不要误食。
Objective:To investigate the mushroom poisoning cases which led to 81 person poisoning occurred in Deyang,Sichuan province in May 23～June 15,2003.Method:The identification of mushroom species was by means of morphology,the amanita toxic peptides in fruitbodies,blood and dialyser were determined by means of high-performance liquid chromatography(HPLC).Results:The investigation showed that the poisonous mushrooms were mainly Amanita kotohiraensis Nagasawa & Mitani.The detemiantion of toxins displayed that Amanita kotoihiraensis contained two lethal amatoxins(α-amanitin and β-amanitin),the content of α-amanitin and β-amanitin in fruitbodies were 196.42μg/g,62.76μg/g dried fruitbodies respectively.The blood contained trace β-amanitin and the dialser did not contain any toxins.Conclusion:Amanita kotohiraensis was a poisonous mushroom.
出处
《现代预防医学》
CAS
北大核心
2005年第1期3-4,31,共3页
Modern Preventive Medicine
基金
湖南省科技厅课题 (0 3JZY3 0 2 6)
