多原发肺癌诊治的临床体会及文献回顾

Clinical experience and bibliography retrospection of multiple primary lung cancer

目的结合临床体会及文献回顾探讨多原发肺癌的诊断及手术治疗。方法对11例诊断为多原发肺癌患者的临床病例资料进行回顾性分析。男9例,女2例。同时性双原发肺癌5例,异时性双原发肺癌6例,按肿瘤不同的生长部位采取不同的手术方式,8例采用规范的肺叶切除术;3例因肺功能差行肿物切除术。结果本组无手术死亡,10例获得随访,失访1例。存活1年8例(占72.7%),存活3年4例(占36.4%),存活5年1例(占9.1%),现有2例仍在随访中。结论手术切除为多原发肺癌的主要治疗方法,肺癌术后应防止治疗过度或化疗周期过长。

Objective:To analyze the diagnosis and surgical treatment of multiple primary lung cancer.Methods:The clinical data of 11 cases of multiple primary lung cancer were analyzed retrospectively,9 males and 2 females.5 cases developed bilateral synchronous lung cancer and 6 cases developed metachronous multiple primary lung cancer.Different operative procedures were adapted to the various growing sites of tumor,8 cases with normative pulmonary lobectomy, 3 cases with lump resection for the poor pulmonary function.Results:All cases were successful,10 cases were in follow-up,1 case was out of follow-up.8 patients survived one year (72.7%),4 patients survived 3 years (36.4%),1 patient survived 5 years (9.1%),2 patients were still in follow-up.Conclusion:Operative treatment is the key therapy for multiple primary lung cancer.Excessive treatment and long course of chemotherapy should be prevented after operation.