神经外科医院感染部位及病原体的临床分析

Susceptible Sites and Pathogens of Nosocomial Infection in Neurosurgery: A Clinical Analysis

目的 探讨神经外科医院感染的易感部位、病原体的构成及药敏 ,指导临床合理治疗。方法 回顾性调查我院近 3年来神经外科住院患者的有关临床资料 ,对确诊医院感染 32 0例患者的主要病原体进行药敏试验测定。结果 神经外科医院感染的易感部位依次为下呼吸道、泌尿道、中枢神经系统及切口 ;细菌学检查共检出医院感染病原菌 737株 ,为铜绿假单胞菌 (196株 ,占 2 6 .5 9% )、金黄色葡萄球菌 (15 0株 ,占 2 0 .35 % )、肺炎克雷伯菌(10 5株 ,占 14 .2 5 % )位居前 3位。结论 耐药菌株是医院感染的主要病原体 ,采取相应预防措施 ,定期行药敏实验 ,依据药敏实验调整用药 。

OBJECTIVE To explore the susceptible sites, composition and drug-sensitivity of nosocomial infection in neurosurgery department so as to get reasonably clinical treatment. METHODS Correlative clinical data of 320 inpatients in neurosurgery department were retrospectively investigated in recent 3 years. The drug-sensitivity test was done for all cases of nosocomial infection. RESULTS The susceptible sites for neurosurgical nosocomial infection were lower respiratory tract, urinary tract, central nervous system and surgical section in order. A total of 737 pathogens were found in bacteriological detection. The Pseudomonas, Staphylococcus and TBXKlebsiella pneumoniae were the most common pathogens in order. CONCLUSIONS The main pathogens are drug-resistant bacteria. A satisfactory effect could be got through taking prevention measures according to various correlative factors and using antibiotics according to drug susceptibility test.