早期梅毒开始治疗时间及血清反应素初始滴度与疗效的关系

The Relations among Beginning Time of Treatment, Initial Titre of Serum Reagin and Gurative Effect in Early Syphilis Cases

目的 :了解早期梅毒患者开始治疗时间及血清反应素初始滴度与疗效的关系。方法 :分析我科性病门诊 2 44例确诊为早期梅毒患者的临床资料 ,采用相关分析方法 ,分析其开始治疗时间及血清反应素初始滴度与平均阴转时间的线性相关关系。结果 :早期梅毒患者的血清滴度与阴转时间具有正相关关系 ,r=0 .874,P <0 0 1 ;开始治疗时间与阴转时间具有线性相关关系 ,r=0 771 ,P <0 0 1 ;开始治疗时间与初始血清滴度亦呈线性相关关系 ,r=0 5 74,P <0 0 5。结论 :早期梅毒病人的血清抗体滴度阴转时间与其病程。

Objective:To find out the relationship among beginning time of treatment, initial titre of the serum reagin and the curative effect in early syphilis cases. Methods:The clinical data were collected from 244 out-patients with early syphilis in our STD clinic. The linear correlation of beginning time of treatment, initial titre of serum reagin and average seronegative time in the patients were analyzed. Results:The serum titre and the seronegative time of patients with early syphilis presented positive correlation, r=0.874, P<0.01; the beginning time of treatment and the duration of seronegative in the patients presented positive linear correlation, r=0.771, P<0.01; between the beginning treatment time and initial titre of serum reagin also presented positive correlation, r=0.574, P<0.05. Conclusion:The seronegative duration of initial titre of serum reagin in early syphilis patients presented positive correlation with the course, the severity of the disease and their beginning treated time.