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胸腺肽治疗白癜风临床疗效观察 被引量:4

Clinical Study on Effect of Thymus Peptide in Treatment of Patients with Vitiligo
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摘要 目的 :观察胸腺肽治疗白癜风的疗效。方法 :83例患者被随机分成治疗组 ( 5 0例 )和对照组( 3 3例 )。治疗组 5 0例 ,应用胸腺肽治疗 (皮损内注射 ) ,对照组 3 3例 ,采用白蚀丸、维乐生片 ,外搽 1 5 %补骨酯酊治疗。结果 :治疗组总有效率为 78% ,而对照组为 3 0 3 0 % (P <0 0 1 )。结论 Objective:To observe the therapeutic effect of thymus peptide in treatment of patients with vitiligo. Methods:83 patients with vitiligo were randomly divided into the treatment group (50 patients) and the control group (33 patients). 50 patients of the treatment group were treated with thymus peptide and injected in skin lesions. 33 patients of the control group were treated with baishiwan, weileshengpian and 15% buguzhiding.Results:The total effective rate of treatment group and control group were 78% and 30.30% (P<0.01) respectively. Conclusion:These results suggested that vitiligo patients treated with thymus peptide could get better effects.
出处 《岭南皮肤性病科杂志》 2003年第4期251-252,共2页 Southern China Journal of Dermato-Venereology
基金 广州市科委重点攻关科研课题 :98-Z -117-0 1
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  • 1全国中西医结合皮肤性病学会色素病学组.白癜风临床分型及疗效标准(草案)[J].中华皮肤科杂志,1995,28(4):212-212.
  • 2Goldstein AL, Low TL, Mcadoo M, et al. Thymosin alphal:isolation and sequence analysis of an immunologically active thymic polypeptide. Proc Natl Acad Sci USA, 1997,74:725 -729.
  • 3Mutchnick MG, Prieto JA, Schaffue JA, et al. Thymosin modulation of regulatory T cell function. Clin Immunol Immunopath,1982,23: 626.
  • 4Nastino A, Fanavi C, Grea S, et al. Thymic hormones and cytokins. Int J Immunopathol Pharmacolgy, 1992,5:77.

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