手性在锆原子上的二茂锆配合物的合成

Study on the Synthesis of Chiral Zirconocenes with Chirality on the Zirconium Atom

由新?基环戊二烯和三甲基硅基环戊二烯制备了两个前手性的二茂锆配合物。由它们与亲核试剂的反应,合成了一些新的,手性在锆原子上的锆配合物。~1H NMR和^(13)C NMR谱图表明,配体上的手性基团对锆原子上的取代反应有明显的手性诱导效果。

From (+)-neomenthylcyclopentadiene and trimethylsilyl cyclopentadiene, a couple ofprochiral zirconocenes have been prepared. Upon further reactions with nucleophiles thesezirconocenes were transformed to chiral ones with chirality on the zirconium atom. TheNMR spectra of these complexes manifested that the chiral ligand had exerted a considerable chirally inductive effect during the course of the nucleophilic substitution.