摘要
目的 :恶性肿瘤化疗的同时联合应用促红细胞生成素 (EPO) ,观察对癌症相关性贫血 (MTA)临床症状的改善效果。方法 :观察组在化疗前 1周开始给予EPO ,对照组只进行化疗不用EPO ,其他辅助治疗两组相同 (包括营养支持、粒细胞刺激因子应用、出血者止血药物的应用、重要脏器的保护等 )。结果与结论 :化疗联合用EPO能预防和治疗MTA。对靠输血提升血红蛋白后化疗的患者可明显减少输血量 ,甚至可停止输血。
OBJECTIVE:To observe the result of improvement on clinical symptom of MTA by malignant tumor chemotherapy combined with EPO.METHODS: Observing grou p began to use EPO one week before chemotherapy, control group only perform che motherapy without EPO, other adjunctive therapy in two groups were same (includ ing nutritional support, use of granulocyte stimulating factor, anastaltic for the patients with hemorrhage and protection of important organs).RESULTS & CO NCLUSION:Chemotherapy combined with EPO can prevent and treat MTA, obviously decrease blood transfusion quantity in the patients depending on blood transfusi on to increase hemoglobin during chemotherapy and even stop blood transfusion. EPO has certain effect on treatment of MTA and prevention of anemia caused by ch emotherapy.
出处
《中国医院用药评价与分析》
2003年第6期354-355,共2页
Evaluation and Analysis of Drug-use in Hospitals of China