氧疗对全麻后睡眠期脉搏血氧饱和度的影响

Effect of oxygen therapy on SpO_2 after general anesthesia during sleep.

目的 观察全麻后睡眠期氧疗的效果和低氧血症发生的时间。方法 6 0例ASAⅠ～Ⅱ级、年龄 2 5～ 84岁的患者随机分为睡眠期氧疗组和睡眠期非氧疗组 ,每组 30例。全麻苏醒拔管回病房后 ,Venturi面罩给氧 (FiO2 =31 % ) ,氧疗组持续 72h ,而非氧疗组在睡眠期则停止吸氧。观察手术前夜和术后第 1、2、3夜的脉搏血氧饱和度 (SpO2 )值 (S0 、S1 、S2 、S3 )。结果 氧疗组S2 低于S0 (P <0 .0 5 ) ,非氧疗组S1 和S2 明显低于S0 (P <0 .0 1 ) ,S3 低于S0 (P <0 .0 5 )。两组同时间比较 ,非氧疗组S3 低于氧疗组 (P <0 .0 5 ) ,且非氧疗组的S1 和S2 明显低于氧疗组的对应值 (P <0 .0 1 )。结论 全麻后睡眠期可发生低氧血症 ,氧疗能明显提高患者的SpO2

Objective To observe the effect of oxygen therapy on hypoxaemia during sleep after general anesthesia. Methods Sixty patients aged between 25～84 years (ASA Ⅰ～Ⅱ) were divided randomly into oxygen therapy group ( n 1=30) and non oxygen therapy group ( n 2=30). Oxygen were inspired by Venturi mask for both groups (FiO 2=31%): Oxygen therapy group lasted for 72 h, while non oxygen therapy group stopped inspiring oxygen during sleep. SpO 2 values of the preoperative night (S 0), the first (S 1), the second (S 2) and the third (S 3) night after general anesthesia were recorded.Results S 2 was lower than S 0 in oxygen therapy group ( P < 0.05 ). S 1, S 2 and S 3 were significantly lower than S 0 in non oxygen therapy group ( P < 0.01 or P < 0.05 ), and S 1, S 2 and S 3 in non oxygen therapy group were significantly lower than those of oxygen therapy group at the same time.Conclusion Oxygen therapy for the patients during sleep after general anesthesia can elelvate the SpO 2 value.