老年脑梗塞血小板膜Ts含量与血脂血糖及血钙相关分析

Correlation between Blood Platelet Membrane Ts Content and Blood Lipid,Blood Sugar,Blood Calcium in Patients with Senility Cerebral Infarction

目的：研究５０例老年急性脑梗塞患者血浆中血小板膜凝血酶敏感蛋白（Ｔｈｒｏｍｂｓｐｏｎｄｉｎ，Ｔｓ）与部分生化指标改变的相关性，有利于制定急性脑梗塞早期防治措施。方法：采用流式细胞仪测定Ｔｓ，生化指标用５０８型生化自动分析仪检测。结果：脑梗塞组血浆中血小板膜Ｔｓ与甘油三酯胆固醇、血糖、血钙相关良好，相关系数分别在０．３３、０．３４、０．３１、０．５６以上，Ｐ＜０．０５。而脑动脉硬化组相关系数分别为０．１４、０．１６、０．０７、０．０７，Ｐ＞０．０５。结论：Ｔｓ是血小板膜上α－颗粒蛋白，表达于激活后血小板表面，血浆中Ｔｓ含量增高值与上述生化指标正相关性改变参与脑梗塞形成机制。

Objective:We researched fifty example of patients with acute cerebral infarction,and studied the correlation of blood platelet membrane thrombspondin(Ts)and any biochemical criterion in them.It is favourable to the early stage of acute cerebral infarction prevention and cure.Methods:We measured Ts with FCM(flow cytometry),bioch emical criterion with 508 type automatic biochemistry analysor.Results:A positive relationship between the blood platelet membrane Ts and trigly ceride,Cholesterol,blood sugar,blood cacium in the group of cerebral infarction.The relationship quotient is 0.33、0.34、0.31 、 0.56 respectively in the groups of cerebral in farction,P<0.05.The relationship quotient is 0.14、0.16、0.07、0.07 respectively in the groups of patients with ecrebral atherosclerosis.Conclusions:Ts is a kind of granule protein in platelet membrane,it is expression in surface of activated platelet.The variobly of the positive relitionship between Ts and above biochemical criterion influence infarction.