脑梗塞患者血小板活性的动态观察

Dynamic Observetion of Platelet Activlty in 40 Cerebral in Farction Patients

目的：观察脑梗塞患者血小板α－颗粒膜蛋白的变化。方法：用放免法测定４０例脑梗塞患者及２０例健康者对照血小板表面及血浆内α－颗粒膜蛋白值。结果：正常对照血小板Ｇｍｐ－１４０６５０±１８０分子数／血小板，血浆Ｇｍｐ－１４０１１．７±１．９μｇ／ｍｌ，４０例脑梗塞患者Ｇｍｐ－１４０９６３±３０２分子数／血小板，血浆Ｇｍｐ－１４０３９．４±１４．９μｇ／ｍｌ。二者有显著差异。结论：脑梗塞患者血小板活性增高。

Objective:To observe the variety of platelet α-granule membrane protein in patients with cerebral infarction(CI).Methods:Platelet membrane and Plasma α-granule membrane protein were detected by radioimmunoassay in 40 CI And 20 healthy controls.Results:Platelet membrane and plasma Gmp-140 in CI patients and healthy controls were 963±302/platelet,39. 4±14.9μg/ml,650±180/platelet,11.7±1.9μg/ml.Gmp-140 in CI patients was significantly higher than that in normal individuals.Conclusions:It is suggested that platelet activity increases in cerebral infarction patients.