陈旧性脊髓损伤的中枢痛中自发痛的特性及可能的发生机制(待续)

Character and possible mechanism of spontaneous pain of Long-term central pain in spinal cord injury

采用ＭｃＧ：１１疼痛答卷对陈旧性脊髓损伤中枢痛患者１２例的自发痛的特点及其对生活、睡眠的影响进行了观察，将其分为三组、两型，并发现其与睡眠有一定的关系。于自发间断痛发作时（Ｓ１），持续麻木痛存在时（Ｓ２）及无痛时（Ｓ３）测定正中神经的体感诱发电位２４人次，发现在８０－１００ＭＳ处出现Ｎ１Ｐ１波，三组间波幅两两比较Ｓ１＞Ｓ２（Ｐ＜０．０１），Ｓ１＞Ｓ３（Ｐ＜０．０１）。这一结果初步揭示陈旧性脊髓损伤中枢痛中自发痛的特性，并为其可能的传导通路及发生机制提供了依据。

This work carried out observation to the character and the influence of the spontaneous pain of long-term central pain in 12 SCI patients to daily ;living and sleeping.We classified the pain into3kinds,2 types,and found that spontaneous pain has some relation withsleeping.We also determined somatosensory evoked potentials of median nerve 24 person-time,when they suffered from spontaneous constant pain(S1),continuous numb pain(S2)and no pain(S3).The results showed;there is N1P1 wave in 80 to 100ms of SEP.The comparing resuit of amplitude of three groups is S1>S2(P<0.01),S1>S3(P<0.01). These results preliminarily revealed the character of the pain,and provided basis for its possible conductive pathway and occurrence mechanism.