摘要
我们曾报道从浙贝母(Fritillaria thunbergii Miq.)的鳞茎中分离到3种新生物碱——浙贝宁、浙贝丙素和浙贝酮,以及已知的浙贝甲素、浙贝乙素和 eduardine。进一步深入研究时,又分离到两种化合物,分别鉴定为浙贝宁甙(zhebeininoside,Ⅰ)和苦鬼臼毒素(picropodophyllotoxin,Ⅱ)。化合物Ⅰ为新的生物碱甙,化合物Ⅱ在该属植物中首次得到。
In our previous papers,it was reported that peimine,peiminine,eduardine and three new alkaloids,zhebeinine,zhebeirine,zhebeinone,were isolated from the bulbs of Fritillaria thun- bergii Miq..In consecutive investigation of the plant,an additional new alkaloidal glucoside, 5α,14α-cevanine-6α,20β-dihydroxyl-3β-O-β-D-glucoside,named zhebeininoside(Ⅰ)and a known picropodophyllotoxin(Ⅱ)were isolated.The structure of zhebeininoside was deter- mined on the basis of spectral analysis and chemical reaction.Picropodophyllotoxin was fir- stly isolated from Fritillaria plants.
基金
国家自然科学基金资助课题
关键词
浙贝母
化学成分
贝母
Fritillaria thunbergii Miq
Zhebeinine
Zhebeininoside
Picropodophyllotoxin
