长梗绞股蓝皂甙化学成分的研究

Studies on the Saponin Constituents of Changgeng Jiaogulan (Gynostemma longipes)

从长梗绞股蓝Ｇｙｎｏｓｔｅｍｍａ ｌｏｎｇｉｐｅｓ中，用大孔树脂、硅胶柱层析和薄层层析制备方法，分离到４个化合物，其中２个化合物（皂甙Ｉ和Ⅱ），根据＾１３ＣＮＭＲ、ＦＡＢ－ＭＳ和ＭＳ确定为新化合物。皂甙Ｉ为３β，１９－醛基，２４－甲基，２２，１６－环氧达玛烷３－Ｏ－β－Ｄ－吡喃木糖基－（１→２）－β－Ｄ－吡喃木糖甙，命名为长梗绞股蓝皂甙Ａ。皂甙Ⅱ为３β，２３－二羟基，１９－醛基，２４－甲醛基。

Two new saponins（Ⅰ and Ⅱ）were isolated by macroPorous resin D-101 and sio2 column chromatography and preparative TLC from Gynostemma longipes C. Y. Wu collected in the range of An kang in China. Their structures were elucidated on the basis of spectral data of FAB-MS, EI-MS, 13CNMR and IR, as 3β, 23-hydroxy-19-oxo-24-methyl-22, 16-epoxy-dammar-3-O-β-D-xylo-pyranosyl（1→2）-β-D-xylopyranoside（gylongoside A） and 3β, 23-hydroxy-19-oxo-24-methyl-22, 16-epoxy-dammar-3-O-α-L-rhamnopyranosyl-（1→2）-β-D-xylopyranosyl-（1→2）-β-D-xylopyran-oside （gylongoside B） respectively.