伴肌炎病变的嗜酸性筋膜炎7例临床及活检

A study of 7 cases of myositis wish eosinophilic fasciiatis

全部病例在肢体和部分躯干皮肤筋膜呈弥漫性肿胀变硬,手上举有桔皮样外观和沿静脉走向坑道状凹陷,诉无力,肌肉疼痛和肌萎缩,其邻近筋膜显著硬化,有前臂和掌屈肌腱鞘呈坚硬条索、肢体病变处关节挛缩。活检证实7例的胶原纤维明显增生和纤维化,纤维间和血管周围有淋巴细胞、浆细胞及少量嗜酸粒细胞浸润,4例肌外膜增厚,5例肌纤维轻度变性,肌膜,肌纤维和血管周围均可见到炎性细胞浸润。

There were diffuse swelling and induration of fasci in extremities and trunk in all cases. Experienced malaise, muscular pain and atrophy in varying degree. The neighbouring fascia appeared markedly fibrotic. Histopathologic examintion of cutaneous fascia revealed marked proliferation of collagenous fibers and fibrosis. There was an interfibrous and perivascular infiltration of lymphocytes, plasma cells, eosinophils. 5 cases showed muscular degeneration.