摘要
培养的家兔腹腔巨噬细胞分泌巨噬细胞源生长因子(macrophage-derived growth factor,MDGF),可刺激平滑肌细胞(smooth muscle cells,SMC)增生,经用钙通道阻滞剂作用于被MDGF刺激的SMC,则其增生反应即被明显抑制(P<0.05)。
Cultured rabbit peritoneal macrophages could produce and secrete a growth-stimulatory factor (MDGF) that could stimulate the growth of cultured SMC in vitro(P<0.05); while calcium channel blockers (verapamil and nifedipine) could inhibit the pro-liferation of SMC stimulated by MDGF (P<0.05).
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
1993年第2期231-235,共5页
Chinese Journal of Pathophysiology
关键词
细胞
钙拮抗剂
动脉粥样硬化
Muscle,smooth,vascular
Monocytes
Macrophages
Calcium channel blockers
Atherosclerosis
