摘要
饲克山病病区粮大鼠红细胞膜(RBCM)锌(Zn)含量与饲非病区粮大鼠比较锌含量显著降低,而镁(Mg)含量却显著增加,钙(Ca)含量亦增加,同时伴以红细胞(RBC)变形能力的显著降低和血浆脂质过氧化物(LPO)水平的显著升高。相关分析结果表明,饲病区粮大鼠血浆脂质过氧化物水平增高可能与 RBCM—Zn 含量降低有关。
The results were that the contents of Zn on red blood cell membrance(RBCM-Zn)of rats fed on grains from a Keshan endemic area were lower significanly than from unendemic area,but the contents of Caand Mg were higher;at the same time,red cell deformability(RCD)reduced significantly and level of lipi-doperoxide in plasma increased significantly.With correlation analysis these results indicated that the increaseof lipidoperoxidation of rats fed on grains from a Keshan disease endemic area was related to reduce ofRBCM-Zn contents.
出处
《中国地方病学杂志》
CAS
CSCD
1993年第2期68-71,共4页
Chinese Jouranl of Endemiology
关键词
克山病
微量元素
红细胞膜
Keshan Disease
Trace Elements
Red Blood Cell Membrane
Red Cell Deformability
Lipidoperoxidation
