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The synthesis of potential anticancer drugs related to mitoxantrone

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摘要 ABSTRACT In an attempt at a rational design for anticancer drugs, two new potential anticancer compounds related to mitoxantrone were prepared. Compounds 4. 1.4-dihydroxy-6-aminoethyl-9.10-anthracenedione was synthesized in 6 steps starting with 4-methyl-phthalic acid, and compound 5, 2(4-aminobutyl)-l 4-dihvdroxv-9,10-anthracenedione was synthesized in 5 steps from N-3-bromopropylphthalimide.
作者 ZhengWei JamesLBloomer
机构地区 DepartmentofChemistry
出处 《中国抗生素杂志》 CAS CSCD 北大核心 2001年第2期112-117,共6页 Chinese Journal of Antibiotics
关键词 ANTICANCER DRUGS MITOXANTRONE New COMPOUNDS
分类号 R914.2 [医药卫生—药物化学]
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参考文献7

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中国抗生素杂志
2001年 第2期

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