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卡马西平对男性癫痫患者雄性激素水平的影响 被引量:1

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摘要 38%~71%男性癫痫患者,可出现生殖内分泌功能异常,表现性欲下降、性功能减退等[1].其原因是多方面的,除了社会、精神因素外,癫痫和抗痫药物(AEDs)的作用也不能排除.目前国内外对癫痫患者生殖内分泌变化的研究较多[1~3],但多为多药联合治疗.本研究通过测定单用卡马西平(CBZ)治疗的男性癫痫患者血清中的雄性激素水平,观察用药时间与雄性激素的关系,探讨其发生改变的原因,从而为临床治疗提供依据.
作者 王雁 谭兰
出处 《神经疾病与精神卫生》 2001年第1期38-39,共2页 Journal of Neuroscience and Mental Health
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参考文献7

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同被引文献15

  • 1禇春民,张桁忠,朱亚琳.苯巴比妥治疗对男性癫患者血清性激素水平的影响[J].中华男科学杂志,2007,13(8):749-750. 被引量:2
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  • 3Xu Xiaotian, Zhang Hengzhong, Xu Yao. Effects of an- tiepileptic drugs on reproductive endocrine function, sexual function and sperm parameters in Chinese Han men with epilepsy [J] . J Clin Neu , 2013, 20: 1492-1497.
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  • 6Crebelli. Threshold mediated mechanisms in mutagnesis : implications in the classification and regulation of chemi- cal mutagens[ J]. Muta Res ,2000,464( 1 ) :129-135.
  • 7Shetty akhila, Jagadish, Narayana K. The effects of car- bamazepine on sperm morphology in wistar rats [ J ]. In- dia J Phy Phar,2007,51 (3) :255-260.
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  • 10Rattya J, Turkka J, Pakarinen A J, et al. Reproductive endocrine effects of valproate, carbamazepine and oxcar- bazepine in men with epilepsy [ J ]. Neurology, 2001, 56 : 31-36.

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