摘要
目的:探讨D-二聚体检测在DIC、溶栓治疗、恶性肿瘤及乙型肝炎等疾病中应用的临床价值。方法:收集40例正常对照组和71例病例组,均采用D-二聚体试剂盒进行检测,检测原理为胶乳凝集试验。结果:各检测组D-二聚体水平显著高于对照组(P<0.01)。结论:D-二聚体检测对DIC、溶栓治疗、恶性肿瘤及乙型肝炎疾病的诊断、治疗及疗效观察提供一定的依据。
Objective: To investigate clinical value of D - Dimer in diseases including Disseminated Intravascular Coagulation(DIC), dissolve thrombus therapy, malignant neoplasm and Hepatitis B. Methods: 71 cases of disease (13 cases of DIC, 20 cases of dissolve thrombus therapy, 18 cases of malignant neoplasm and 20 cases of Hepatitis B) and 40 cases of normal control were collected. D- dimer in all cases was determined by latex agglutination test method. Results: All cases of normal control were negtive for D- Dimer. The positive rates of D - Dimer in DIC,dissolve thrombus therapy, malignant neoplasm and Hepatitis were 92. 3% ,85.0% ,61.1% ,45.0% respectively. The results showed that D - dimer content in the patient group was significantly increased than that in normal control group(P < 0.01). Conclusion: D - dimer examination could provide evidence for clinical diagnosis and treatment in all diseases studied. It could be used as an useful index for observing cure effectiveness in diseases with DIC , dissolve thrombus, malignant neoplasm and Hepatitis B.
