摘要
目的:建立用高效液相色谱法测定氨苄西林的方法。方法:采用YMC—ODS—AQ柱,流动相为水—乙腈—1M磷酸二氢钾—1M醋酸(862:130:7:1),检测波长254nm。结果: 线性范围在0.2～1.8mg·ml^(-1)(r=0.9997),平均回收率99.8％,RSD为0.54％。结论:该方法简便,结果准确,适用于该制剂的质量控制。
Objctive: To establish a HPLC Method for determination ot amp(?) capsules. Method: C_(18) column was used, mobil phase was water—acetonittile- 1mol/L potassium dihydrogenphosphate—1mol/L acetic acid(862: 130: 7: 1), detection wavelength was 254nm. Results: The Detection ranges were 0.2—1.8mg/ml. The average recovery of ampieillin was 99.8%(n=0.54%). Conclusion: The method is simple, convenient and accurate.
出处
《中国药品标准》
CAS
2000年第3期57-58,61,共3页
Drug Standards of China
