摘要
目的探讨老年人与青年人胃癌不同的临床特点。方法收集本院1981年—1996年住院手术治疗,经病理检查确诊的胃癌1086例,按年龄不同分为老年组(≥60岁)373例,青年组(≤35岁)52例,比较两组的临床病理指标。结果老年组男:女为3.22:1,青年组为1:1.89;老年组肿瘤位于胃窦部以上占66.5%,青年组肿瘤多位于胃窦部,占78.8%;老年组中高分化腺癌占62.2%,而青年组中低分化、未分化及粘液腺癌居多,占73%;老年组手术切除率为75.5%,青年组为59.6%;老年组5年生存率为49.8%,青年组为15.4%。结论老年人和青年人胃癌具有不同的临床特点,应加以区别对待;但由于青年人胃癌较老年人胃癌发病年龄早,预后更差,应引起重视。
Objective To research the different clinical characleristics between the old and young pa- tients with gastric carcinoma.Methods One thousand and eighty-six patients with gastric carcinoma,who underwent surgical treatment in our unit from 1981 to 1996,were divided into the old patient group (age≥ 60 yrs) and young patient group(age≤35 yrs).The clinicopathological factors were analysed between the two groups.Results The ratio of male to female was 3.23 to 1 in the old patient group and 1 to 1.89 in the young patient group.The tumors located in the upper portions of the stomach (including cardia,fundus, corpus) were 66.5% in the old patient group,while 21.2% in the young patient group.The well differen- tiated adenocareinoma were 62.2% in the old patient group,but only 11.5 % in the young patient group, respectively.5-year survival rate was 49.8% in the old patient group and only 15.4% in the young patient group.Conclusions There are different clinicopathological characteristics between the old and young patient with gastric carcinoma,and different treatments should be carried out between them.Moreover,more atten- tion should be paid to the young patients with gastric carcinoma because the tumors occur earlier and the prognosis are poorer in the young patients than in old ones.