冠心病患者基础C-反应蛋白与颈动脉粥样硬化的关系

The association between basic C-reactive protein and cervical atherosclerosis in patients with coronary artery disease

目的 探讨炎症标志物C-反应蛋白(CRP)与颈动脉粥样硬化的关系.方法 对120例冠心病患者(A组)和30例年龄匹配的健康志愿者(B组),分别行CRP检测和颈动脉超声检查,计算斑块指数,比较其相关性.结果 A组CRP明显高于B组,分别为(5.27±3.85)mg/L和(2.18±3.40)mg/L,P<0.01;A组斑块指数明显高于B组,分别为(4.51±2.75)和(1.24±0.37),P<0.01;冠心病组CPR与斑块指数呈正相关,r=0.36,P<0.01,差异有显著性意义.结论 冠心病患者CPR明显高于对照组,可反映颈动脉粥样硬化的程度.

Objective To explore the association between inflammatory sign named C-reactive protein (CRP) and cervical atherosclerosis. Method 120 coronary artery disease patients (Group A) and 30 healthy subjects with similar age (Group B), received CPRP concentration examination and cervical artery ultrasonography evaluation, plaque index was calculated, then compared the correlativity of them. Result CRP cncentration in grup A was significantly higher than that of group B. They were (5. 27±3. 8)mg/L and (2. 18±3. 40)mg/L,P<0. 01. Plaque index in group A was significantly higher than that of group B,They were (4. 51±2. 75) and (1. 24±0. 37) P<0. 01. They was positive relation between CRP concentions and plaque index of patients with coronary artery disease,s=0. 36,P<0. 01. There was significant difference in the report. Conclusion CRP concentration of patients with coronary artery disease was significantly higher than that of the healthy subjects, it can evaluate the cervical atherosclerosis.