摘要
本文的主要目的是测定非感染性梗阻黄疸患者与感染性梗阻性黄疸患者血清TNF生物学活性,并分析患者肝功指标与TNF活性间的可能关系。本研究共分为对照组、非感染性梗阻性黄疸组及感染性梗阻性黄疸组。结果提示:1.梗阻性黄疸患者血清TNF生物学活性升高,而感染可能是其升高的主要原因;2.TNF生物学活性升高,可能是引起梗阻性黄疸患者肝脏功能恶化的一个重要因素。
This study was designed to detect the serum tumor necrosis factor(TNF) biological activity in patients with non-infectious obstructive jaundice, and in patients with infectious obstructive jaundice, and to analyze the possible relations between hepatic function indexes and TNF biological activity. Patients were divided into three groups: control group, non-infectious obstructive jaundice group and infectious obstructive jaundice group. Results indicatd: 1. The serum TNF biological activity tvas increased in patients with obstructive jaundice, and infection might bee an important reason; 2. The increased TNF biological activity might be an important factor for the worsened hepatic function in patients with obstructive jaundice.