摘要
对30例急性颅内压增高症患儿通过放射性免疫方法进行血浆胃动素水平的测定,与30例正常健康儿童对照比较。结果表明、急性颅内压增高症患儿血浆胃动素水平为575.02±350.52pg/mI,较正常健康儿童的水平(C278.87±77.81pg/ml)明显提高(P<0.01)。急性颅内压增高患儿伴昏迷及消化道症状者显著升高(p<0.01)。急性颅内压增高患儿伴昏迷及消化道症状时,血浆胃动素水平较非昏迷及无消化道症状时,血浆胃动素水平较非昏迷及无消化道症状者显著升高(p<0.01),死亡者比存活者胃动水平高(P<0.01)。疾病恢复期血浆胃动素水平较急性期显著下降,与健康儿童比较差异不显著(p>0.05)血浆胃动素水平可以作为判断病情轻重及预后的指标。
To detect the Level of serum motilin in 30 cases with acute intracranial hypertension by radio activity immunity method,comparing with 30 normal children.The results showed that the value of motilin in acute intracranial hypertension was significantly increased(575.02±350. 52Pg/ml),than the controt group(278.87±77.81Pg/ml)(p<0.01).when children of cute in- tracranial hypertension had coma or gastrointestinal symptoms,the value or motilin was increased greatly(p<0.01),There had higher motilin in the dead than in the living(p<0.01).value of- motilin in recovery period was more decreased than acute period.The results suggested that the level of serum motilin could act as one of the factors by judging the degree and prognosis of acute intracranial hypertension.