摘要
目的 了解ACE抑制剂对高血压患者室性心律失常的影响,并初探机理.方法 对36例高血压患者用ACE抑制剂治疗前后对照研究,并设21例对照组.结果 治疗组的室性心律失常及Lown’s 3～4级病例数明显减少(P<0.005),同时与左室肥厚的逆转相关(r=0.614,P<0.05).结论 ACE抑制剂治疗可减少高血压病人的室性心律失常,并认为逆转心室肥厚可能是其机制之一.
[Abstract] Objective To analyse the relationship between the changes of ventricular arrhythmias and treatment with ACE Inhibitors in hypertensive patients. Methods 36 cases treated with ACE Inhibitors served as test group, other 21 cases as control group, both groups were tested before and after treatment .Results VPCs and incidence of Lown' s Grade III & IV after treatment with ACE Inhibitors were obviously less than before, associated with LVMI reducing. Conclusion ACE Inhibitors might decrease ventricular arrhythmias by reducing the increased cardiac hypertrophy.
