摘要
本文报告复方海蛇胶囊(R.S.C.)双盲法治疗398例中、老年记忆减退(包括健忘症)(MQ<100者294例)的临床试验结果。用药分为R.S.C.组与空白对照组,均为每次3粒胶囊,每粒0.28克,每日3次,疗程2个月。以WMS评定疗效。R.S.C.治疗前与治疗后MQ分别为91.3±17.3及101.4±18.8(P<0.001)。对照组治疗前后分别90.6±165及94.5±17.1(P<0.05)。R.S.C.与对照组治疗后复查MQ增值分别为10.63±11.71及3.95±8.28(t=6.5261,P<0.001)。两组总有效率分别为58.80%及38.46%(P<0.001)。本组未见明显副作用。
The clinical trial of RSC (0.28g/ cap) was performed by double blind method on 398 patients with hypomnesis (MQ of 294 cases< 100). The mean values of MQ (WMS) in the treated (mean age 73.7±5.4 yrs) and the control (mean age 71.7±5.7 yrs) groups were 91.3±17.3 and 90.6±16.5 (P>0.05) respectively. The dosage is 0.28gx 3 tid for 2 months. After the treatment, the mean MQ values of treated and control groups were 101.4± 18.8 and 94.5±17.1 with the MQ increase of 10.63±11.71 and 3.951±8.29 respectively (t=6.5261,P<0.001). The total effective rates were 58.8% and 38.46% (Ridit x2 = 23.86, P<0.01) in the two groups. No significant side effects were observed.
出处
《老年医学与保健》
CAS
1996年第1期5-8,共4页
Geriatrics & Health Care
基金
上海市科技发展基金
编号:944112002