骨矿含量与骨折相关性及其骨折危险阈值研究

The correlation between bone density and fracture and the threshold limit value of bone mineral density to screen population at high risk of fracture

本文测量了８２例骨折病人和１７１例正常人的桡骨骨矿含量，结果表明：骨折病人的骨矿含量显著低于正常人；用ｌｏｇｉｓｔｉｃ回归来分析骨矿含量与骨折危险性之间的关系，结果表明骨矿含量与骨折危险性呈负相关，骨矿含量每下降０．１ｇ／ｃｍ２，骨折危险性增加１倍。以骨折危险性高于２０％为骨折高危人群，则男性骨折危险阈值为０．５８ｇ／ｃｍ２，女性骨折危险阈值为０．５４ｇ／ｃｍ２。

Bone mineral density in radius was measured in 82 cases of fracture and in 171 normal subjects. The results showed that bone mineral density in patients was significantly lower than that in normal subjects. The relationship between bone mineral density and risk of fracture was analysed by logistic regression ,showing that the risk of fracture was inversely related to bone mineral density. As bone mineral density decreased by 0. 1g/cm2,the risk of fracture increased by two times. The threshold limit value(TLV)of bone mineral density to screen the population at more than 20% risk of fracture in men was 0. 58g/cm2,and the TLV in women was 0. 54g/cm2.