峰值骨量及影响因素在骨质疏松诊断中价值的探讨

Importance of Peak bone mass and its influential factors to diagnosis of osteoporosis

为了对骨质疏松进行诊断，必须建立自己实验室的峰值骨量正常值，并应考虑到对峰值骨量的各种影响因素。本文采用ＳＰＡ和ＤＥＸＡ，测定了中国３６８７９人群的挠骨、尺骨中远１／３部位的骨矿密度（ＢＭＤ）及股骨近端（股骨颈、大转子，ＷＡＲＤ’Ｓ区）ＢＭＤ。通过其中所测１０９７５人群上述部位的结果建立了峰值骨量的正常值，峰值骨量的年龄段是在２０～３９岁。本文在讨论中与国内外不同作者进行了对比，并分析了影响峰值骨量的各种因素，以便在诊断骨质疏松时恰当使用峰值骨正常值。

A normal value of peak bone mass (PBM)should be established to diagnose osteoporosis correctly according to individual data of one's laboratory findings and its influential factors should be taken into account. In a series of 36879 Chinese, we measured bone mineral density(BMD)of distal 1/3 part of radius and ulna and proximal part of femur (collum ossis femoris, trochanter major, Ward's region)through SPA and DEXA(XR-26). Baed on 10975 peoples' BMD of above parts, we set up a normal value of PBS and the PBM age bracket is 20～39. We compared the results with those of other researchers' and home and abroad and analyzed the factors which influence the value of PBM, so as to utilize the normal value effectively in diagnosing osteoporosis.