绝经后骨质疏松患者的缺钙和补钙的作用

Effect of calcium supplementation on postmenopausal osteoporotic patients

２４例绝经后骨质疏松症患者分两组进行了钙平衡试验，年龄５６．３１±２．９９和５８．６６±４．２６，绝经年限１２．５±７．１１和１０．７７±４．５６，该组妇女平均食物钙摄入４２２．６ｍｇ／日，未补钙者平均负钙平衡１２．８８ｍｇ／日，补钙５００ｍｇ／日者平均正钙平衡３１８．２２ｍｇ／日，摄入钙的利用率占３３％，经２年单纯补钙，ＱＣＴ腰椎骨密度增高１３％，低钙摄入的妇女单纯补钙有一定预防骨质疏松的作用。

Twenty-four postmenopausal osteoporotic patients were divided in to two groups, 12 in each group. The ages for groups A and B were 58. 66±4. 26 and 56. 31±2. 99 years, respectively, and the menopausal terms were 12. 5±7.11 and 10. 77±4. 56 years, respectively. Group A underwent one calcium balance test only and then were given calcium 500 mg daily for 7 days. Group B underwent two calcium balance tests, one after taking calcium 500mg daily for one year. For group B, the average calcium intake from food was 422. 6mg/d and the average positive calcium balance was 318. 22 mg/d. For group A, the average negative calcium balance was 12. 88mg/d.The availability rate of calcium intaken for group B was 33%. After calcium supplememtation for two years, the lumbar vertebral bone density measured by QCT increased about 13%. It suggests that for women with low calcium intake, calcium supplementation alone can prevent postmenopausal osteoporosis.