摘要
目的:研究表明,胆汁返流性胃炎有严重的胃排空障碍,本文着重探讨胃窦平滑肌电生理水平上的改变在胆汁返流性胃炎中可能的发病意义。方法:对13例胆汁返流性胃炎(R组),10例非胆汁返流性胃炎(N组)和7名健康志愿者(C组)的胃窦平滑肌电连续检测30分钟以上,比较平均慢波频率和胃节律紊乱的发生率和节律异常的严重程度。结果:各组平均慢波频率无显著性差异,但三组均可见胃节律异常,发病率在R组较高,为53.8％(7/13),C组和N组较低,分别为14.3％(1/7)和30.0％(3/10);程度上R组>N组>C组。结论:严重的胃窦平滑肌电节律紊可能是胆汁返流性胃炎发病的一个重要因素。
Objective:Our previous study revealed that patients with bile reflux had severe delay of gastric emptying. In this study, we investigated the possible role of antral dysrhythmias in the pathogenesis of the disease. Methods: Antral myoelectric activities were measured in 13 patients with bile reflux gastritis (group R), 10 patients with non-reflux gastritis (group N)and 7 healthy controls (group C) for at least 30min. Freqencies of slow waves more than 5 cpm,or less than 2 cpm,or irregular activities lasting for more than 1 rain were diagnosed as dysrhythmia. Parameters of mean slow wave freqencies (MSWFs,cpm)and dysrhythmias were compared among 3 groups. Results: MSWFs showed no significant difference among 3 groups, while oecurence of dysrhythmias was higher in group R(7/13,53.8％) than group N (3/10,30％) and group C(1/7,14.3％). Further analysis of severity of dysrhythmias displayed that severe disorders of myoelectric activities were seen in group Rand group N,mild in group C. Conclusios: Severe dysrhythmias in antrum may be of significant importance in pathogenesis of bile reflux gastritis.
