摘要
作者对36例功能性消化不良(FD)患者进行西沙比利试验治疗,另外随机选择10例作为对照。结果表明反流型、运动紊乱型FD效果明显;而溃疡型FD效果较差,其中有2例在服药后腹痛加重,改为5mg后,腹痛缓解。该药的总有效率为83.3％,效果良好者达79％。本文结果提示,西沙比利对全胃肠道的作用优于吗丁啉。
We treated 36 cases functional dyspepsia (FD) patients using Cisapride and compared the effect to other 10 FD patients treated with placebo. The results showed that the reflux and dysmotire type FD responsed signigicantly, but the ulcer-like type FD reponsed poorly, in ulcer-like group 2 cases were worse compared with before when the medicine dose was 10mg/time, but when the medicine was reduced to 5mg/time the abdominal pain remitted. The response of ulcerlike FD in our study was no difference to that of Canadian Cisapride group. The total effective rate was 83.3%, significantly effective rate was 79%. Our results suggest that effect of Cisapride was better than that of Domperidone to whole gastrointestinal tract.
