摘要
本文的目的在于探讨在健康老年人中,甲状旁腺素(PTH),钙(Ca)、磷(P)、镁(Mg)、碱性磷酸酶(AKP)、肌酐(Cr)与骨密度(BMD)之间的关系。选择70名健康老人,抽血查C-PTH、Ca、P、Mg、AKP和Cr的水平。并在左侧桡骨远端1/3处,用单能光子骨密度测定仪测定BMD。以正常参考值为标准(0.6297~0.7695g/cm2),将对象分为BMD降低组和BMD正常组。结果显示:(1)在BMD正常组(BMD值为0.73±0.07g/cm2)中,PTH的水平为155.36±93.45(ng/L),在BMD降低组(BMD值为0.57±0.04g/cm2)中,PTH的水平为214.11±91.93(ng/L)。二组间差异有统计学意义。(2)在BMD正常组中,血清钙的水平为2.12±0.22(mmol/L),在BMD降低组中,血清钙的水平为2.23±0.19(mmol/L)。两组相比,差别有统计学意义(P<0.05)。实验结果提示:在老年男性与年龄有关的骨密度降低中,PTH的分泌起到重要作用。
This study aimed to determine the relationship between parathyroid hormone(PTH) ,calcium(Ca), phosphorus (P), alkaline phosphatase(AKP) and bone mineral density(BMD). In 70 healthy old men, blood samples were drawn for measurment of PTH ,Ca, P, AKP et al. BMD was measured at left radius by mono-energy X-ray absorptiometry. According normal reference parameter (0.6297-0.7695),all subject were divided into BMD low group and BMD normal group. The results shown; (1)The level of PTH was 155.36±93.45(ng/L)in BMD normal group (BMD:0.73+0. 07g/cm2) and was 214.11±91.93(ng/L)in BMD low group(BMD:0. 57±0. 24g/cm2). The difference was significantly between two groups (P<0. 05). (2)The level of serum Ca was 2.12±0. 22 (mmol/L) in BMD normal group and was 2.23±0.19(mmol/L)in BMD low group. The difference was significantly between two groups(P<0.05). Our results suggest a role of PTH in the decrease of BMD.
出处
《中国骨质疏松杂志》
CAS
CSCD
1995年第2期92-93,91,共3页
Chinese Journal of Osteoporosis