实验性小肠扭转中谷氨酰胺的应用

Effect of Glutamine in Experimental Small Intestinal Volvulus

本实验通过实验性小肠扭转模型,观察了小肠缺血半小时后再灌注,在应用超氧化物歧化酶进行保护的基础上,再应用谷氨酰胺一周后大白鼠小肠粘膜湿重,脱氧核糖核酸含量及肠粘膜形态学改变。结果表明,应用谷氨酰胺后能促进肠粘膜细胞的分裂增殖,加速损伤粘膜的增生修复。

By the model of experimental small intestinal volvulos. We observed the mucos-al weight, the content, of Deaxyribonuclease (DNA) and the morphology change of the cat intestinal mucosal that reperfusion after ischemiaed for half a hour followed by apply Glulamine (GLN) for a weed after applied superoide Dismutase (SOD). The results showed that Glutamine aueterates healing of intestinal mucosal after ischemia-reperfusion injcory