老年人血清过氧化脂质测定及有关因素分析

DETERMINATION OF SERUM LPO IN 560 ELDERLY AND ANALYSIS OF RELATED FACTORS

560例老年人、147例中青年血清过氧化脂质(LPO)测定结果显示、LPO 值随增龄而升高,与年龄呈正相关,其中20～、50～两组与各年龄组,60～与50～、80～、90～104三组有显著差异.70岁后各年龄组无差异。健康组与冠心病,急性心肌梗塞,糖尿病三疾病组,按血脂质分类的正常和高血脂组之间,均有显著差异。80岁后老年人,不论有无慢性疾病或血脂异常与否LPO 值无明显差异。本文结果提示 LPO 是了解体内自由基代谢的良好指标。

The results showed that the level of lipid peroxidate(kPO)in serum determinated in 560 cases in aged group and 147 cases in young and middle age group was increased with age,and significant differnce was showed among 20～,50～,age groups and other age groups, (60 and 50～,80～,90～ 104 age groups),no difference among old persons aged 70 and over.Comparsion the control with disease group including coronary disease,acute myocardiac infarction,diabetes mellitus,and hyperlipemia and normal lipemia group in the elderly showed significant difference expect age group 80 years and over with disease or not.The results suggested that LPO is a good biomark- er for research on metabolism of free radical in the elderly.