慢性乙型肝炎患者环一磷酸腺苷含量和淋转率关系的研究

Research on Relation between cAMP and LIT in Patients with Chronic Hepatitis B.

同步检测30名慢性乙肝患者和15名正常成人的淋巴细胞转化率(LTT)和淋巴细胞内环一磷酸腺苷(cAMP)含量,结果显示慢性乙肝患者的LTT较正常人降低,其(?)±s分别为80.58±22.43和107.91±42.15(P<0.05)。而慢性乙肝患者的cAMP较正常人显著升高,分别为3.34±0.93和2.34±0.55(P<0.05)。慢性乙肝患者LTT和CAMP之间呈负相关关系r=-0.39,P<0.05,而正常对照组两者的相关关系无显著性。检测慢性乙肝患者的LTT和cAMP均有助于了解其细胞免疫状态。

cAMP and LTT of 30 patients with chronic hepatitis B (CH) and 15 normal persons were detected. The resuls showed the LTT of patients were lower than those of normal persons, (80.58±22.43 vs 107.91±42.15, P<0.05). But the cAMP of patiente were higher than those of normals (3.34±0.93 vs 2.34±0.55, P<0.05). LTT and cAMP in CH had high significant inverse correlation (r=-039, P<0.05). The results may be helpful in understanding the body's immune stage.