血清刀豆素A结合蛋白的检测及其临床意义

MEASUREMENT OF SERUM ConA-CONJUGATED PROTEIN AND ITS CLINICAL SIGNIFICANCE

将外源性凝集索ConA与血清中糖蛋白相结僵，在电泳上可形成峰，根据峰的高低可测定血清中所谓ConA结合蛋白含量。正常人血清中ConA结合蛋白为95．16±14．54u／dl，慢性肝病时降低，肝细胞性肝癌时升高。本法简便，灵敏度高。初步显示测定血清中该种蛋白有助于肝病的鉴别诊断。

Concanavalin-A(ConA), a kind of lectin, when combined with the serumglucoprotein, may form a peak in the electrophoresis. According to the heightof the peak, we are able to detect the amount of ConA-conjugated protein. Innormal individuals, the serum level is 95.16%±14.54u/dl, It decreases in chro-nic liver diseases and increases in hepatocellular carcinoma. This method isboth simple and sensitive. The assay for this kind of serum protein is prelimi-narily shown to be helpful in the differential diagnosis of liver diseases.