摘要
本文报告由进口平缝机组装件橡胶罩所致职业性接触性皮炎。199例缝纫工中104例(52.3%)发病。潜伏期1~3周。皮损多限于右膝外侧直接接触橡胶处,甚至波及同侧大小腿或呈对称分布。临床表现与非职业性接触性皮炎相似,伴剧痒。临床调查与斑试结果表明橡胶罩及防老剂IPPD为主要变应原。部分未患皮炎的接触者也对上物呈阳性反应,提示已发生潜在过敏现象。结合接触组发病率高、潜伏期短,不能完全除排致病物本身刺激作用在发病中的影响。
Among 199 workers, 104(52.3%)developedcontact dermatitis at the lateral surface ofthe right knee by direct contact to rubbercover of imported sewing machine. The dermatitis occurred after exposure for1--3 weeks, and essentially limited at the late-ral surface of the right knee, and may spreadto the leg in severe cases. The patients had atypical lesion of contact dermatitis with severeitching. Discontinuing the exposure plus symp-tomatic treatment mitigated the dermatitis. Re-exposure triggered the recurrence of dermatitisand made it difficult to heal. Patch tests were taken in 48 patients and13 'healthy' exposurers. Forty-two patients(87.6%) reacted positively to 1~6 kinds ofpatch test material, among which mostly tothe surface layer of the rubber cover (83.3%),followed by 0.5% antioxidant IPPD and 0.5~1% antioxidant TMDQ (47.9 %). The reac-tion, especially of TMDQ, which spread overthe patch, was strong. However, among 13 'healthy' exposures,38.5% reacted to 1% TMDQ, 15.4% to therubber cover, and 15.4% to 0.5% IPPD, indi-cating the existence of potential hypersensiti-vity and irritation.
出处
《中国工业医学杂志》
CAS
1989年第4期5-7,64,共3页
Chinese Journal of Industrial Medicine