摘要
对72例轻度铅中毒、44例铅吸收及7例接触铅无铅中毒住院患者测定了PbB、CPbU(驱铅治疗第一日的尿排铅量)、ALAU、FEP、ZPP。微机分析结果指出不同病情的3组病例之间,5项指标都有极显著的差异,并高度相关,可以相互换算。相关分析表明曲线回归优于直线回归。FEP的升高程度大于ZPP。FEP与ZPP的优点是在慢性铅中毒很少出现假阴性,测定结果的稳定性较好,简便迅速而易于操作。缺点是接触铅后并不迅速升高,临床治愈后并不迅速恢复,测定结果与病情不平行,特异性也不够,评价时应注意这些不足之处。
The blood lead (PbB) and urine lead atthe first day with chelating agents (CPbU) andurine δ--aminolevulinic acid (ALAU), free ery-throcyte protoporphyrin (FEP), and zincprotoporphyrin (ZPP) were determined among72 cases of mild lead poisoning, 44 cases oflead absorption, and 7 cases of exposed nor-mals. The relationship among the parametersmentioned-above were found by the regressionanalysis using microcomputer. It is indicatedthat the model of curve regression was betterthan that of linear regression. The increasegrade of FEP was greater than that of ZPP,as PbB increase. The diagnostic value of the Parametersmentioned above in lead poisoning was dis-cussed. When FEP and ZPP were used, thefalse negativity (of the diagnosis) was verylow and reliability was very high. However,the FEP and ZPP levels were not related tothe clinical manifestation and the results oftreatment. The specificity of FEP and ZPPwere not satisfactory.
出处
《中国工业医学杂志》
CAS
1989年第4期8-11,64,共4页
Chinese Journal of Industrial Medicine
