摘要
本表研究采用甲状腺上动脉、静脉、中静脉及下动脉分支的上支结扎,断其血供;保留下静脉及下动脉下支,保证保留下极内侧少部分腺体血供回流,并在其上动脉、下动脉分支切断腺体端动脉腔内置管灌注乙醇,利用动脉结扎失去血供后,乙醇易于流动,注入后能迅速弥散到甲状腺内小动脉中,导致小血管痉挛,内皮损伤,管壁肿胀,组织变性。使小动脉形成永久性闭塞,不致发生侧枝血管形成,致闭塞区域的甲状腺组织逐渐出现变性、萎缩纤维化、失去分泌功能,而被保留的少部分腺体分泌维持正常生理功能,达治愈甲亢之目的。36例治疗结果和动物实验表明,此方法简单、安全可靠、行效确切、并发症少、不复发,适合于广大基层医院开展。
I his study adopted section of the upper thyroid vessels, middle thyroid vein and the upper twig of lower thyroid artery. The lower thyroid vein and lower twig of the lower thyroid vein were pre-served. The blood supply of the inner portion of thyroid gland was retained. An extradural tube was inserted into the distal cut end of the arteries respectively, through which certain amount of ethylalcohol was then injected. The injected alcohol can be easily poured into the tiny arterioles with resulting spasm of the arterioles and damage of its intima as well as swelling of the vascular wall. The animal experiment showed permenant blockage of the poured vessels without any formation of collaterals. The poured thyroid tissue showed gradual shrinking, fibroatrophy and loss of secretion activity. The reserved small portion of thyroid tissue will still functioning normally. The result in 30 patients of Graves disease thus treated and the animal experiment showed that the technique was simple and safe, reliable and curative without complication and relapse. It will suit primary hospitals for treatment of Graves disease.
