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支气管哮喘患者血浆环核苷酸的变化及其临床意义

Changes of Plasma CAMP,CGMP in Patients with Bronchial Asthma
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摘要 应用放射免疫分析法(RIA)对26例支气管哮喘患者哮喘发作期和缓解期分别进行血浆环磷酸腺苷(CAMP)和环磷酸鸟苷(CGMP)含量测定,结果表明哮喘发作期血浆CAMP和CGMP均明显低于健康对照组(分别P<0.01),缓解期CGMP恢复正常,而CAMP仍处于较低水平。提示气道炎症性变化在哮喘缓解期并未完全消失,仍有复发的可能性,应设法提高细胞内CAMP的含量可望从根本上缓解哮喘病。 Plasma levels of CAMP. CGMP in 26 patients with bronchial asthma were measured by RIA. The results showed that values of CAMP, CGMP in patients with active asthma break - out stage than those in healthy controls(P < 0.01) ;and in relax stage the level of CGMP was recovered to normal,while that of CAMP still was in lower level. It is suggested that inflammatory changes in the airway were not totally vanished in the relax stage; while there existed the possibility of relapse. By increasing level of CAMP in the cells could be cured radicaly.
出处 《解剖与临床》 1997年第3期122-123,共2页 Anatomy and Clinics
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  • 1罗文侗.支气管哮喘研究进展及存在问题[J]中华结核和呼吸杂志,1995(03).

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