儿童单纯性肥胖对健康危害的配对研究

STUDY OF SIMPLE OBESITY’S DAMAGE ON CHILDREN’S HEALTH

目的 :研究儿童单纯性肥胖对健康的危害。方法 :用配对 t检验及逐步回归分析方法对单纯性肥胖儿童的形态、机能及生化指标等进行了分析。结果 :配对分析时显示 :肥胖儿童的体重、皮脂厚度、体块指数、体脂率、收缩压、舒张压、胆固醇 (TC)、甘油三酯 (TG)、血糖、胰岛素、低密度脂蛋白 -胆固醇 (L DL - ch)动脉硬化指数 (AI)高于对照组 (均 P <0 .0 5 ) ;相关分析时 ,体块指数与胰岛素、 TG呈中度正相关 ;体重与胰岛素呈中度正相关 ;逐步回归分析时 ,胰岛素、 TG、收缩压与体块指数呈正相关 ;胰岛素、收缩压、 TG与体重呈正相关 ,高密度脂蛋白 -胆固醇 (HDL - ch)与体重呈负相关。结论 :单纯性肥胖儿童存在患高胰岛素血症、高血压、糖尿病。

objective:To understand damage on the health of children causedby simple obesity Methods: A paired T test and stepwise regression were used to analyse morphological, physiological and biochemical indexes of simple obesity children Results: The body weight, sebaceous thickness, body mass index (BMI) and body fat rate of obesity children were significantly higher than those of control group (P<0 001) The systolic pressure, diastolic pressure, cholesterol, triglyceride, blood sugar, insulin, LDL C and AI in the case group were also higher than those in control group (P<0 05) There was medium correlation among between BMI and insulin and triglyceride respectively, and medium correlation between body weight and insulin The stepwise regression indicated that the variate relative to BMI were insulin, triglyceride and systolic pressure The variate relative to body weight were insulin systolic pressure, triglyceride and HDL C Conclusion: Simple obesity children had the risk of hyperinsulinemia, hypertension, diabetes, hyperlipemia and atherosclerosis