具抗癌活性的鬼桕毒电子自旋标记物的生物学作用——研究Ⅰ.对细胞生长的抑制试验

Study on Biological Function of Spin-Labeled Anticancer Podophyllotoxin Derivatives——I . The Inhibition for the Growth of Cells

用鬼桕毒自旋标记衍生物对子宫颈癌细胞(Hela)、乳地鼠肾传代细胞(BHK)和人胚肺成纤维细胞(KMB)进行了体外抑制试验,发现鬼桕毒自旋标记衍生物在用量为0.1mg时,对Hela、BHK细胞有较强的抑制作用。

Hela KMB and BHK cells are found to be inhibited in vitro by spin labeled podophyllotoxin derivatives. By means of trypan blue staining, we have found that podophyllotoxin derivatives at a dose of 0. 1 mg bears considerable effect on cells of Hela and BHK.