摘要
目的：评价美托洛尔对高血压左心室肥厚的逆转作用。方法：对56例高血压左心室肥厚的患者用美托洛尔25～200 mg/d，治疗12周后进行观察。结果：用美托洛尔25～200 mg/d治疗后，血压平均下降(3．73/1．33±0．667/0．400)kPa。治疗后室间隔厚度(LVST)、左心室后壁厚度(PWT)、左室重量指数(LVMI)均有明显减少(均为P<0．01)。结论：显示美托洛尔能有效降压，并有逆转左心室肥厚作用。
To evalute the effect of metoprolol on lef t ventricular hypertrophy reversal Methods:56 patients with essential hypertension complicated wi th left ventricular hypertrophy were treated with metoprolol for 12 weeks Result:After treatment with metoprolol,the patients' blood pre ssure was reduced,IVST,PWT and LVMI were decreased (P<0.01) Conclusion:Metoprolol was effective in treatment of hypertensi on and reversed left ventricular hypertrophy
